Fabrication and Characterization of Microwire Electrochemical Paper-based Analytical Devices with Quasi-steady Flow

A new approach for incorporating metallic microwire electrodes into simple, self-pumping paperbased microfluidic devices is presented. The low resistance wire electrodes improve electrochemical response relative to screen-printed carbon electrodes. Here, for the first time, microwire electrodes have been incorporated into a self-pumping quasi-steady state flow paper-based microfluidic device capable of flow injection analysis with enhanced signal response due to constrained flow within the paper device.